منابع مشابه
GPC1 Regulated by miR-96-5p, Rather than miR-182-5p, in Inhibition of Pancreatic Carcinoma Cell Proliferation
To determine the relationships between miR-96-5p/-182-5p and GPC1 in pancreatic cancer (PC), we conducted the population and in vitro studies. We followed 38 pancreatic cancer patients, measured and compared the expression of miR-96-5p/-182-5p, GPC1, characteristics and patients' survival time of different miR-96-5p/-182-5p expression levels in PC tissues. In an in vitro study, we investigated ...
متن کاملPlasma miR-15b-5p, miR-338-5p, and miR-764 as Biomarkers for Hepatocellular Carcinoma
BACKGROUND Recently, increasing research evidence indicates that miRNA plays important roles in oncogenesis of hepatocellular carcinoma (HCC). The objective of this study was to investigate the potential of plasma miRNAs as biomarkers for HCC determination. MATERIAL AND METHODS This trial included 4 phases: (i) miRNAs in tumor tissues were screened with a miRNA array for determining candidate...
متن کاملمطالعه تغییرات بیان mir-411-5p و mir-299-5p در آدنوکارسینومای معده
چکیده: سرطان معده یکی از علل مرگ ومیر در جهان و به خصوص در کشورهای آسیایی می باشد. میکرو rna ها،rna های کوچک غیر کد کننده به طول 20-24 نوکلئوتید هستند که در تنظیم بیان ژن بعد از رونویسی نقش دارند. میکرو rna ها قادر به اتصال به ناحیه ترجمه نشدنی 3 ژن هدف هستند. این اتصال سبب تخریب mrna یا مهار ترجمه می شود. میکرو rna های بسیاری تاکنون در سلول های انسانی شناسایی شده است که در مراحل مختلف رشد و نم...
Differential expression of miR-1297, miR-3191-5p, miR-4435, and miR-4465 in malignant and benign breast tumors
Objective(s): MicroRNAs (miRs) are a class of small non-coding RNAs which are associated with tumor growth and progression. In the present study, we assessed the expression of selected miRs in malignant, benign, and adjacent normal breast tissues. Materials and Methods: The expression of miR-1297, miR-3191-5P, miR-4435, and miR-4465 were...
متن کاملThe clinical significance of downregulation of mir-124-3p, mir-146a-5p, mir-155-5p and mir-335-5p in gastric cancer tumorigenesis.
Dysregulated miRNAs in gastric cancer are usually screened by miRNA microarray from clinical samples, however, reports have indicated that results of each miRNA microarray screening are considerably different, and dysregulated miRNAs, especially downregulated miRNAs were contradictory. In view of this, the Human Cancer Pathway Finder miRNA PCR array was applied to compare 7 gastric cancer cell ...
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ژورنال
عنوان ژورنال: Medicine
سال: 2021
ISSN: 0025-7974,1536-5964
DOI: 10.1097/md.0000000000025808